Journal article
Enantioselective organocatalytic Michael additions to acrylic acid derivatives: generation of all-carbon quaternary stereocentres.
- Abstract:
- Acrylic esters, thioesters and N-acryloyl pyrrole have been identified as effective electrophiles in the enantioselective Michael addition reaction with beta-keto ester pro-nucleophiles catalysed by a cinchona alkaloid derived bifunctional organocatalyst; enantiomeric excesses of up to 98% and yields of up to 96% can be obtained for a range of Michael acceptors and pro-nucleophiles.
- Publication status:
- Published
Actions
Access Document
- Publisher copy:
- 10.1039/b805233f
Authors
- Journal:
- Chemical Communications More from this journal
- Issue:
- 32
- Pages:
- 3798-3800
- Publication date:
- 2008-08-01
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
- Language:
-
English
- Pubs id:
-
pubs:34342
- UUID:
-
uuid:0715a1e7-6ede-4e18-8654-95ba16fddd3b
- Local pid:
-
pubs:34342
- Source identifiers:
-
34342
- Deposit date:
-
2012-12-19
- ARK identifier:
Terms of use
- Copyright date:
- 2008
If you are the owner of this record, you can report an update to it here: Report update to this record