AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings.

Journal article

AIDSand#x2010;associated Cryptococcus neoformans and Penicillium marneffei coinfection has not been adequately studied and poses unique therapeutic challenges in resourceand#x2010;limited settings. Itraconazole poorly penetrates the central nervous system, whereas fluconazole has poor activity against P. marneffei. We prospectively report management of 1 patient and retrospectively review 7 coinfection cases from Vietnam.

Authors: Le, T; Hong Chau, T; Kim Cuc, N; Si Lam, P; Manh Sieu, T

• Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
• Volume: 51
• Issue: 9
• Pages: e65-e68
• Publication date: 2010-11-01
• DOI: 10.1086/656685
• EISSN: 1537-6591
• ISSN: 1058-4838
• Language: English
• Keywords: Humans; Retrospective Studies; Itraconazole; Fluconazole; AIDS-Related Opportunistic Infections; Diagnosis, Differential; Vietnam; Antifungal Agents; Penicillium; Adult; Male; Developing Countries; Cryptococcus neoformans; Prospective Studies; Mycoses