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Assessment of Streptococcus pneumoniae pilus islet-1 prevalence in carried and transmitted isolates from mother-infant pairs on the Thailand-Burma border

Abstract:

Streptococcus pneumoniae pilus islet-1 (PI-1)-encoded pilus enhances in vitro adhesion to the respiratory epithelium and may contribute to pneumococcal nasopharyngeal colonization and transmission. The pilus subunits are regarded as potential protein vaccine candidates. In this study, we sought to determine PI-1 prevalence in carried pneumococcal isolates and explore its relationship with transmissibility or carriage duration. We studied 896 pneumococcal isolates collected during a longitudin...

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Authors


Melchiorre, S More by this author
Moschioni, M More by this author
Barocchi, MA More by this author
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Journal:
Clinical Microbiology and Infection
Volume:
18
Issue:
10
Pages:
970-975
Publication date:
2012-10-05
DOI:
EISSN:
1469-0691
ISSN:
1198-743X
URN:
uuid:0700af42-9adc-4a38-83c8-d773c64c7af2
Source identifiers:
352692
Local pid:
pubs:352692

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