Cyclosporin for severe ulcerative colitis does not increase the rate of perioperative complications.

Journal article

PURPOSE: Cyclosporin is used in severe ulcerative colitis that is refractory to intravenous steroids. Cyclosporin is a potent immunosuppressant and can cause side effects such as opportunistic infections. This study aimed to investigate the incidence of perioperative complications in patients treated with intravenous cyclosporin and steroids compared with patients treated with intravenous steroids alone. METHODS: We retrospectively reviewed the case notes of 44 patients with severe ulcerative...

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Authors: Hyde, G; Jewell, D; Kettlewell, MG; Mortensen, N

• Publication status: Published
• Journal: Diseases of the colon and rectum
• Volume: 44
• Issue: 10
• Pages: 1436-1440
• Publication date: 2001-10-01
• DOI: 10.1007/bf02234594
• EISSN: 1530-0358
• ISSN: 0012-3706
• Language: English
• Keywords: Immunosuppressive Agents; Steroids; Adult; Postoperative Complications; Colitis, Ulcerative; Cyclosporine; Colectomy; Ileostomy; Female; Middle Aged; Retrospective Studies; Infusions, Intravenous; Humans; Anti-Inflammatory Agents; Intraoperative Complications; Male; Acute Disease