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Circulating red cell-derived microparticles in human malaria

Abstract:

In patients with falciparum malaria, plasma concentrations of cell-derived microparticles correlate with disease severity. Using flow cytometry, we quantified red blood cell-derived microparticles (RMPs) in patients with malaria and identified the source and the factors associated with production. RMP concentrations were increased in patients with Plasmodium falciparum (n = 29; median, 457 RMPs/μL [range, 13-4,342 RMPs/μL]), Plasmodium vivax (n = 5; median, 409 RMPs/μL [range, 281-503/μL]), a...

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Publisher copy:
10.1093/infdis/jiq104

Authors


Nantakomol, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Krudsood, S More by this author
Udomsangpetch, R More by this author
Pattanapanyasat, K More by this author
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Journal:
Journal of Infectious Diseases
Volume:
203
Issue:
5
Pages:
700-706
Publication date:
2011-03-01
DOI:
ISSN:
0022-1899
URN:
uuid:06e8bc2a-e2fa-4fe9-aad6-00bd1bf45625
Source identifiers:
120514
Local pid:
pubs:120514
Language:
English

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