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The genomes of four tapeworm species reveal adaptations to parasitism.

Abstract:

Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat, owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma as examples. The 115- to 141-megabase genomes offer insights into the evolution of parasitism. Synteny is maintained with distantly related blood flukes but we find extreme losses o...

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Publication status:
Published

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Publisher copy:
10.1038/nature12031

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Journal:
Nature
Volume:
496
Issue:
7443
Pages:
57-63
Publication date:
2013-04-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:06deb2a0-d13f-40df-8663-b4314f0c535c
Source identifiers:
404112
Local pid:
pubs:404112

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