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Indefinite survival of neural xenografts induced with anti-CD4 monoclonal antibodies.

Abstract:

Xenografts of neural tissue are usually rapidly rejected when transplanted into the central nervous system of adult recipient animals. This study has examined the cell mediated immune response to both concordant (between closely related species) and discordant (between distantly related species) neural xenografts in the mouse, and has investigated the role of the CD4+ and CD8+ T lymphocyte subsets in this process using monoclonal antibodies specific for the CD4 and CD8 cell surface glycoprote...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Neuroscience More from this journal
Volume:
70
Issue:
3
Pages:
775-789
Publication date:
1996-02-01
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
Language:
English
Keywords:
Pubs id:
pubs:114000
UUID:
uuid:06ddab34-92ed-486e-b4c9-3047f9a9fa7d
Local pid:
pubs:114000
Source identifiers:
114000
Deposit date:
2013-11-17

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