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A survey for the rare blood group antigen variants, En(a-), Gerbich negative and Duffy negative on Espiritu Santo, Vanuatu in the South Pacific.

Abstract:

The people of Vanuatu exhibit several different genetic red cell polymorphisms. Some of these, such as alpha thalassaemia, are thought to have reached a high frequency as a result of selection pressure by malaria. In this study three rare blood group antigen variants, En(a-), Gerbich negative and Duffy negative, which are thought to confer a protective effect against malaria were sought in a sample of 214 (187 in the case of Duffy) from Espiritu Santo, Vanuatu. No individuals bearing these ra...

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Publication status:
Published

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Publisher copy:
10.1159/000154291

Authors


Brindle, PM More by this author
Maitland, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Ganczakowski, ME More by this author
Journal:
Human heredity
Volume:
45
Issue:
4
Pages:
211-214
Publication date:
1995
DOI:
EISSN:
1423-0062
ISSN:
0001-5652
URN:
uuid:06d5e0b7-a227-47b8-a44c-7ab383838361
Source identifiers:
44850
Local pid:
pubs:44850

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