Journal article
Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria
- Abstract:
-
Background
Most amino acids are encoded by multiple synonymous codons. However, synonymous codons are not used equally, and this biased codon use varies between different organisms. It has previously been shown that both selection acting to increase codon translational efficiency and selection acting to decrease codon biosynthetic cost contribute to differences in codon bias. However, it is unknown how these two factors interact or how they affect molecular sequence evolution.
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Genome Biology Journal website
- Volume:
- 19
- Pages:
- 102
- Publication date:
- 2018-07-31
- Acceptance date:
- 2018-06-05
- DOI:
- EISSN:
-
1465-6906
- ISSN:
-
1474-760X
Item Description
- Keywords:
- Pubs id:
-
pubs:856196
- UUID:
-
uuid:06d35b3e-9072-400e-80c1-2bd520f79512
- Local pid:
- pubs:856196
- Source identifiers:
-
856196
- Deposit date:
- 2018-06-06
Terms of use
- Copyright holder:
- Seward and Kelly
- Copyright date:
- 2018
- Notes:
- © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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