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Journal article

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer.

Abstract:

The common single-nucleotide polymorphism (SNP) rs3802842 at 11q23.1 has recently been reported to be associated with risk of colorectal cancer (CRC). To examine this association in detail we genotyped rs3802842 in eight independent case-control series comprising a total of 10 638 cases and 10 457 healthy individuals. A significant association between the C allele of rs3802842 and CRC risk was found (per allele OR = 1.17; 95% confidence interval [CI]: 1.12-1.22; P = 1.08 x 10(-12)) with the r...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddn267

Authors


Pittman, AM More by this author
Carvajal-Carmona, L More by this author
Howarth, K More by this author
Di Bernardo, MC More by this author
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Journal:
Human molecular genetics
Volume:
17
Issue:
23
Pages:
3720-3727
Publication date:
2008-12-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:06cdb54d-9e38-4be7-88d7-80a3cf51f9a3
Source identifiers:
72270
Local pid:
pubs:72270

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