A Change of Hallmark: An Update

Journal article : Review

We review the latest development in non-angiogenic tumours. We focused on the last 3 years except the rarer tumours, for which the papers are older. Following the explanation of the modified hallmark of cancer, inducing angiogenesis and/or accessing vessels, the authors review primary and metastatic tumours growing into lung, liver and brain, plus oral cancer, lymphomas and node metastasis. Also progress in treatment, not many unfortunately, and techniques in non-angiogenic tumours are discussed.

Authors: Donnem, T; Kerr, D; Nikitenko, LL; Pezzella, F

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: MDPI
• Journal: Cells
• Volume: 14
• Issue: 19
• Pages: 1490
• Article number: 1490
• Publication date: 2025-09-24
• Acceptance date: 2025-09-19
• DOI: 10.3390/cells14191490
• EISSN: 2073-4409
• ISSN: 2073-4409
• Language: English
• Keywords: angiogenic; metastases; non-angiogenic; primary; tumours; co-option
• Subtype: Review