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Myocardial metabolism of triacylglycerol-rich lipoproteins in type 2 diabetes.

Abstract:

Cardiac utilisation of very-low-density lipoprotein (VLDL) and chylomicrons (CM) was investigated in the ZDF rat model of type 2 diabetes, in order to define the role of triacylglycerol (TAG) metabolism in the development of contractile dysfunction. Hearts from obese diabetic and lean littermate control rats were perfused with VLDL and CM from diabetic and control rats. Metabolic fate of the lipoprotein TAG and contractile function were examined. Myocardial utilisation of both VLDL- and CM-TA...

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Journal:
Journal of physiology More from this journal
Volume:
587
Issue:
Pt 13
Pages:
3301-3315
Publication date:
2009-07-01
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Language:
English
Keywords:
Pubs id:
pubs:239132
UUID:
uuid:06c63a25-d1ac-4281-bf0e-5df0c3920097
Local pid:
pubs:239132
Source identifiers:
239132
Deposit date:
2012-12-19

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