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The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms

Abstract:

Background: Over the past two decades, the APOE gene and its polymorphisms have been among the most studied risk factors of Alzheimer disease (AD) development; yet, there are discrepancies between various studies regarding their impact. For this reason, the evaluation of the APOE genotype has not been included in the current European Federation of Neurological Societies guidelines for AD diagnosis and management. This aim of this study was to add to this discussion by asse...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13195-016-0187-9

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Sub department:
Psychiatry
Role:
Author, Author
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Role:
Author
ORCID:
0000-0002-4169-9685
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Role:
Author
ORCID:
0000-0002-3634-7562
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Publisher:
Springer Science and Business Media LLC Publisher's website
Journal:
Alzheimer's Research & Therapy Journal website
Volume:
8
Issue:
1
Article number:
19
Place of publication:
England
Publication date:
2016-05-19
Acceptance date:
2016-04-19
DOI:
ISSN:
1758-9193
Pmid:
27193889

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