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Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.

Abstract:

Protein post-translational modifications (PTMs) represent important regulatory states that when combined have been hypothesized to act as molecular codes and to generate a functional diversity beyond genome and transcriptome. We systematically investigate the interplay of protein phosphorylation with other post-transcriptional regulatory mechanisms in the genome-reduced bacterium Mycoplasma pneumoniae. Systematic perturbations by deletion of its only two protein kinases and its unique protein...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/msb.2012.4

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
Publisher:
EMBO Press Publisher's website
Journal:
Molecular systems biology Journal website
Volume:
8
Pages:
571
Publication date:
2012-02-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292

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