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Journal article

ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells.

Abstract:

BACKGROUND: Hashimoto Thyroiditis (H.T.) is a destructive autoimmune thyroid condition whose precise molecular pathogenesis remains unclear. ret/PTC-1 is a chimeric transcript which has been described in autoimmune thyroid disease (AITD) and thyroid neoplasia. The purpose of this study was to observe the immunogenic effect exposure to H.T. and control lymphocyte supernatant would have on normal (Nthy-ori) and ret/PTC-1 (TPC-1) expressing thyroid cell line models. RESULTS: A 2 x 2 matrix comp...

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Publication status:
Published

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Publisher copy:
10.1186/1476-4598-7-44

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
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Journal:
Molecular cancer
Volume:
7
Issue:
1
Pages:
44
Publication date:
2008-01-01
DOI:
EISSN:
1476-4598
ISSN:
1476-4598
Source identifiers:
441495
Language:
English
Keywords:
Pubs id:
pubs:441495
UUID:
uuid:06bd0850-a321-447d-9334-f710059c6a36
Local pid:
pubs:441495
Deposit date:
2013-12-11

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