Journal article
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis
- Abstract:
-
Neural stem cell self-renewal, neurogenesis, and cell fate determination are processes that control the generation of specific classes of neurons at the correct place and time. The transcription factor Pax6 is essential for neural stem cell proliferation, multipotency, and neurogenesis in many regions of the central nervous system, including the cerebral cortex. We used Pax6 as an entry point to define the cellular networks controlling neural stem cell self-renewal and neurogenesis in stem ce...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 5
- Issue:
- 6
- Pages:
- ARTN e1000511
- Publication date:
- 2009-06-12
- Acceptance date:
- 2009-05-12
- DOI:
- EISSN:
-
1553-7404
- ISSN:
-
1553-7390
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:06b1ab75-a08e-41b0-a660-3293ca42e838
- Local pid:
- pubs:482775
- Source identifiers:
-
482775
- Deposit date:
- 2014-09-17
Terms of use
- Copyright holder:
- Sansom et al
- Copyright date:
- 2009
- Notes:
- Copyright: © 2009 Sansom et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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