Journal article icon

Journal article

Epigenetic influences in the developmental origins of osteoporosis.

Abstract:

Osteoporosis is a major public health problem due to consequent fragility fractures; data from the UK suggest that up to 50% of women and 20% men aged 50 years will have an osteoporosis-related fracture in their remaining lifetime. Skeletal size and density increase from early embryogenesis through intrauterine, infant, childhood and adult life to reach a peak in the third to fourth decade. The peak bone mass achieved is a strong predictor of later osteoporosis risk. Epidemiological studies h...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s00198-011-1671-5

Authors


Holroyd, C More by this author
Dennison, E More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Volume:
23
Issue:
2
Pages:
401-410
Publication date:
2012-02-05
DOI:
EISSN:
1433-2965
ISSN:
0937-941X
URN:
uuid:06a51a7c-a794-4d2e-ad41-3d0931cadadd
Source identifiers:
151225
Local pid:
pubs:151225

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP