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Big brains, meat, tuberculosis and the nicotinamide switches: Co-evolutionary relationships with modern repercussions on longevity and disease?

Abstract:

Meat eating has been an important trigger for human evolution however the responsible component in meat has not been clearly identified. Here we propose that the limiting factors for expanding brains and increasing longevity were the micronutrient nicotinamide (vitamin B3) and the metabolically related essential amino-acid, tryptophan. Meat offers significant sourcing challenges and lack causes a deficiency of nicotinamide and tryptophan and consequently the e...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.mehy.2014.04.003

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Publisher:
Elsevier
Journal:
Medical Hypotheses More from this journal
Volume:
83
Issue:
1
Pages:
79-87
Publication date:
2014-04-12
Acceptance date:
2014-04-01
DOI:
EISSN:
1532-2777
ISSN:
0306-9877
Pmid:
24767939
Language:
English
Keywords:
Pubs id:
pubs:463012
UUID:
uuid:06a214ca-0045-49c6-8022-ecea97cc9d76
Local pid:
pubs:463012
Source identifiers:
463012
Deposit date:
2019-08-02

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