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Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's disease

Abstract:

Patients with Parkinson's disease can show brief but dramatic normalization of motor activity in highly arousing situations, a phenomenon often termed paradoxical kinesis. We sought to mimic this in a controlled experimental environment. Nine patients with Parkinson's disease and nine age-matched healthy controls were asked to grip a force dynamometer as quickly and strongly as possible in response to a visual cue. A loud (96dB) auditory stimulus was delivered at the same time as the visual c...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
European Journal of Neuroscience
Volume:
34
Issue:
1
Pages:
124-132
Publication date:
2011-07-05
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
URN:
uuid:0698d27b-1459-4267-9674-15d7ef30563a
Source identifiers:
166797
Local pid:
pubs:166797

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