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Dexamethasone and long-term outcome of tuberculous meningitis in Vietnamese adults and adolescents.

Abstract:

BACKGROUND: Dexamethasone has been shown to reduce mortality in patients with tuberculous meningitis but the long-term outcome of the disease is unknown. METHODS: Vietnamese adults and adolescents with tuberculous meningitis recruited to a randomised, double-blind, placebo-controlled trial of adjunctive dexamethasone were followed-up at five years, to determine the effect of dexamethasone on long-term survival and neurological disability. RESULTS: 545 patients were randomised to receive eithe...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0027821

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
6
Issue:
12
Pages:
Article: e27821
Publication date:
2011-01-01
DOI:
EISSN:
1932-6203
URN:
uuid:0694bfa3-aa1d-4d89-a03f-23041205327e
Source identifiers:
221509
Local pid:
pubs:221509

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