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Disease burden of Group B Streptococcus among infants in sub-Saharan Africa: a systematic literature review and meta-analysis

Abstract:

Background: Group B streptococcus (GBS) is a leading neonatal sepsis pathogen globally. Investment in GBS disease prevention, such as maternal vaccination, requires evidence of disease burden, particularly in high infant mortality regions like sub-Saharan Africa. We aimed to provide such evidence by conducting a systematic literature review and meta-analysis to estimate maternal colonization proportion, GBS disease incidence, and GBS serotype distribution.
Methods: MEDLINE, MEDLINE in p...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/INF.0000000000001233

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Name:
Bill and Melinda Gates Foundation
Grant:
OPP1105076
Publisher:
Lippincott, Williams and Wilkins
Journal:
Pediatric Infectious Disease Journal More from this journal
Volume:
35
Issue:
9
Pages:
933–942
Publication date:
2016-09-01
Acceptance date:
2016-05-26
DOI:
EISSN:
1532-0987
ISSN:
0891-3668
Keywords:
Pubs id:
pubs:624291
UUID:
uuid:0675d5e9-7d7b-4bc9-97ff-14e7f1b1922e
Local pid:
pubs:624291
Source identifiers:
624291
Deposit date:
2016-05-27

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