Journal article
LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis.
- Abstract:
-
OBJECTIVE: Human osteoclast formation from mononuclear phagocyte precursors involves interactions between tumor necrosis factor (TNF) ligand superfamily members and their receptors. LIGHT is a transmembrane protein expressed and shed from the surface of activated T cells. Since activated T cells have been implicated in osteoclastogenesis in rheumatoid arthritis (RA), this study sought to determine whether LIGHT can regulate RANKL/cytokine-induced osteoclast formation, to identify the mechanis...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/art.21821
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Bibliographic Details
- Journal:
- Arthritis and rheumatism
- Volume:
- 54
- Issue:
- 5
- Pages:
- 1451-1462
- Publication date:
- 2006-05-01
- DOI:
- EISSN:
-
1529-0131
- ISSN:
-
0004-3591
- Source identifiers:
-
103867
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:103867
- UUID:
-
uuid:066c4cf4-4be7-4b78-987a-5df83312016a
- Local pid:
- pubs:103867
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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