Physical principles of microbubbles for ultrasound imaging and therapy.

Journal article

Abstract:: Microbubble ultrasound contrast agents have been in clinical use for more than two decades, during which time their range of applications has increased to encompass echocardiography, Doppler enhancement, perfusion studies and molecular imaging, as well as a number of therapeutic applications including drug delivery, gene therapy, high-intensity focused ultrasound treatments and sonothrombolysis. The aim of this article is to review the different types of microbubble agent, their physical behaviour and the mechanisms underlying their effectiveness in imaging and therapeutic applications.

Journal:: Cerebrovascular diseases (Basel, Switzerland) More from this journal
Volume:: 27 Suppl 2
Issue:: SUPPL. 2
Pages:: 1-13
Publication date:: 2009-01-01
DOI:: 10.1159/000203122
EISSN:: 1421-9786
ISSN:: 1015-9770

Language:: English
Keywords:: Microbubbles

Contrast Media

Humans

Ultrasonography, Doppler

Emulsions

Liposomes

Hot Temperature

Thrombolytic Therapy

Free Radicals
Pubs id:: pubs:327735
UUID:: uuid:06631afb-1ad6-45b3-931e-1eec9b2a501e
Local pid:: pubs:327735
Source identifiers:: 327735
Deposit date:: 2013-11-16
ARK identifier:: ark:/29072/ora_06631afb1ad645b3931e1eec9b2a501e

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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