Journal article
Plate tectonics of virus shell assembly and reorganization in phage φ8, a distant relative of mammalian reoviruses
- Abstract:
-
The hallmark of a virus is its capsid, which harbors the viral genome and is formed from protein subunits, which assemble following precise geometric rules. dsRNA viruses use an unusual protein multiplicity (120 copies) to form their closed capsids. We have determined the atomic structure of the capsid protein (P1) from the dsRNA cystovirus Φ8. In the crystal P1 forms pentamers, very similar in shape to facets of empty procapsids, suggesting an unexpected assembly pathway that proceeds via a ...
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Bibliographic Details
- Journal:
- Structure
- Volume:
- 21
- Issue:
- 8
- Pages:
- 1384-1395
- Publication date:
- 2013-08-06
- DOI:
- EISSN:
-
1878-4186
- ISSN:
-
0969-2126
- Source identifiers:
-
418921
Item Description
- Language:
- English
- Pubs id:
-
pubs:418921
- UUID:
-
uuid:065bd587-e1e0-4d92-b525-8ba09ff5cf00
- Local pid:
- pubs:418921
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2013
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