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Cytokine expression in dengue fever and dengue hemorrhagic fever patients with bleeding and severe hepatitis

Abstract:

Dengue is the most common mosquito-borne flaviviral infection in the world today. Several factors contribute and act synergistically to cause severe infection. One of these is dysregulated host immunological mediators that cause transient pathophysiology during infection. These mediators act on the endothelium to increase vascular permeability, which leads to plasma leakage compromising hemodynamics and coagulopathy. We conducted a prospective study to explore the expression of pro- and anti-...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-4812-6334
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-6533-6811
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Institution:
University of Oxford
Department:
External
Role:
Author
ORCID:
0000-0001-5968-2032
Publisher:
American Society of Tropical Medicine and Hygiene
Journal:
American Journal of Tropical Medicine and Hygiene More from this journal
Volume:
102
Issue:
5
Pages:
943-950
Publication date:
2020-03-02
Acceptance date:
2021-01-19
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
32124729

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