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Adherence to antiretroviral therapy and clinical outcomes among young adults reporting high-risk sexual behavior, including men who have sex with men, in coastal Kenya

Abstract:
African men who have sex with men (MSM) face significant stigma and barriers to care. We investigated antiretroviral therapy (ART) adherence among high-risk adults, including MSM, participating in a clinic-based cohort. Survival analysis was used to compare attrition across patient groups. Differences in adherence, weight gain, and CD4 counts after ART initiation were assessed. Among 250 HIV-1-seropositive adults, including 108 MSM, 15 heterosexual men, and 127 women, patient group was not associated with attrition. Among 58 participants who were followed on ART, 40 % of MSM had less than 95 % adherence, versus 28.6 % of heterosexual men and 11.5 % of women. Although MSM gained less weight after ART initiation than women (adjusted difference −3.5 kg/year), CD4 counts did not differ. More data are needed on barriers to adherence and clinical outcomes among African MSM, to ensure that MSM can access care and derive treatment and prevention benefits from ART.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1007/s10461-013-0445-9

Authors



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Funder identifier:
https://ror.org/029chgv08
Grant:
092654/Z/10/A
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Funder identifier:
https://ror.org/01cwqze88
Grant:
P30 AI027757
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Funder identifier:
https://ror.org/05ayv2203


Publisher:
Springer
Journal:
AIDS and Behavior More from this journal
Volume:
17
Issue:
4
Pages:
1255-1265
Publication date:
2013-03-15
DOI:
EISSN:
1573-3254
ISSN:
1090-7165


Language:
English
Keywords:
Pubs id:
pubs:394117
UUID:
uuid:0649d0d0-7cfd-479d-808d-64d489e7ede2
Local pid:
pubs:394117
Source identifiers:
394117
Deposit date:
2013-11-17

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