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A multi-functional imaging approach to high-content protein interaction screening

Abstract:

Functional imaging can provide a level of quantification that is not possible in what might be termed traditional high-content screening. This is due to the fact that the current state-of-the-art high-content screening systems take the approach of scaling-up single cell assays, and are therefore based on essentially pictorial measures as assay indicators. Such phenotypic analyses have become extremely sophisticated, advancing screening enormously, but this approach can still be somewhat subje...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0033231

Authors


Publisher:
Public Library of Science
Journal:
PloS ONE More from this journal
Volume:
7
Issue:
4
Pages:
ARTN e33231
Publication date:
2012-04-10
Acceptance date:
2012-02-06
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:325182
UUID:
uuid:06486a62-5dfe-42ce-8549-fd273f51ae0d
Local pid:
pubs:325182
Source identifiers:
325182
Deposit date:
2013-11-16

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