Journal article
BCR repertoire sequencing: different patterns of B cell activation after two Meningococcal vaccines.
- Abstract:
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Next-generation sequencing was used to investigate the B cell receptor heavy chain transcript repertoire of different B cell subsets (naïve, marginal zone, IgM memory and IgG memory) at baseline, and of plasma cells 7 days following administration of serogroup ACWY meningococcal polysaccharide and protein-polysaccharide conjugate vaccines. Baseline B cell subsets could be distinguished from each other using a small number of repertoire properties (clonality, mutation from germ-line and comple...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, 782.2KB)
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- Publisher copy:
- 10.1038/icb.2015.57
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Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Galson, J
+ National Institute for Health Research Oxford Biomedical Research Centre
More from this funder
Funding agency for:
Kelly, D
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Immunology and Cell Biology Journal website
- Volume:
- 93
- Pages:
- 885–895
- Publication date:
- 2015-06-01
- DOI:
- EISSN:
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1440-1711
- ISSN:
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0818-9641
- Source identifiers:
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523145
Item Description
- Language:
- English
- Pubs id:
-
pubs:523145
- UUID:
-
uuid:06439bbb-5cb2-4f6a-b448-bc24086b4bc8
- Local pid:
- pubs:523145
- Deposit date:
- 2015-11-28
Terms of use
- Copyright holder:
- Australasian Society for Immunology Inc
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Australasian Society for Immunology Inc.
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