- Abstract:
-
CONTEXT: Caveolin-1 (CAV1) is an inhibitor of tissue fibrosis. OBJECTIVE: To study the association of CAV1 gene variation with kidney transplant outcome, using kidney transplantation as a model of accelerated fibrosis. DESIGN, SETTING, AND PATIENTS: Candidate gene association and validation study. Genomic DNA from 785 white kidney transplant donors and their respective recipients (transplantations in Birmingham, England, between 1996 and 2006; median follow-up, 81 months) were analyzed for co...
Expand abstract - Publisher copy:
- 10.1001/jama.2010.356
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- Journal:
- JAMA
- Volume:
- 303
- Issue:
- 13
- Pages:
- 1282-1287
- Publication date:
- 2010-04-05
- DOI:
- EISSN:
-
1538-3598
- ISSN:
-
0098-7484
- URN:
-
uuid:064228af-d247-47e1-84df-8ecb7bdf9c7f
- Source identifiers:
-
176425
- Local pid:
- pubs:176425
- Copyright date:
- 2010
Journal article
Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.
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