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Strain-specific differences in Neisseria gonorrhoeae associated with the phase variable gene repertoire

Abstract:

Background: There are several differences associated with the behaviour of the four main experimental Neisseria gonorrhoeae strains, FA1090, FA19, MS11, and F62. Although there is data concerning the gene complements of these strains, the reasons for the behavioural differences are currently unknown. Phase variation is a mechanism that occurs commonly within the Neisseria spp. and leads to switching of genes ON and OFF. This mechanism may provide a means for strains to express different combi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2180-5-21

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Bacterial Pathogenesis and Functional Genomics Group
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Bacterial Pathogenesis and Functional Genomics Group
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Bacterial Pathogenesis and Functional Genomics Group
Role:
Author
More from this funder
Name:
Wellcome Trust
Funding agency for:
Snyder, L
Publisher:
BioMed Central
Journal:
BMC Microbiology More from this journal
Volume:
5
Article number:
21
Publication date:
2005-04-01
DOI:
ISSN:
1471-2180
Language:
English
Keywords:
Subjects:
UUID:
uuid:0641bf76-dc94-4bdc-859c-cba4d36da4c2
Local pid:
ora:1782
Deposit date:
2008-03-14

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