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Palladium-catalysed cyclisation of N-alkynyl aminomalonates.

Abstract:
Go around in (hetero)cycles! The palladium-catalysed tandem cyclisation/coupling reaction of alkynyl- and alkenyl-substituted aminomalonates leads to highly functionalised pyrrolidines and piperidines in good yield (see scheme). The reaction allows efficient access to a broad range of synthetically valuable building blocks. © 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Publication status:
Published

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Publisher copy:
10.1002/chem.201001951

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Chemistry (Weinheim an der Bergstrasse, Germany)
Volume:
16
Issue:
41
Pages:
12303-12306
Publication date:
2010-11-05
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
URN:
uuid:063d7a40-2d87-4710-9458-6196e3bb336e
Source identifiers:
73314
Local pid:
pubs:73314

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