Palladium-catalysed cyclisation of N-alkynyl aminomalonates.
- Go around in (hetero)cycles! The palladium-catalysed tandem cyclisation/coupling reaction of alkynyl- and alkenyl-substituted aminomalonates leads to highly functionalised pyrrolidines and piperidines in good yield (see scheme). The reaction allows efficient access to a broad range of synthetically valuable building blocks. © 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
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