- Abstract:
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The nucleotide analogue brincidofovir was developed to prevent and treat infections caused by double-stranded DNA viruses. Based on in vitro data suggesting an antiviral effect against Ebola virus, brincidofovir was included in the World Health Organisation list of agents that should be prioritised for clinical evaluation in patients with Ebola virus disease (EVD) during the West African epidemic.In this single-arm phase 2 trial conducted in Liberia, patients with laboratory-confirmed EVD (tw...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.4mb)
-
- Publisher copy:
- 10.1371/journal.pone.0162199
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 11
- Issue:
- 9
- Pages:
- Article: e0162199
- Publication date:
- 2016-09-09
- DOI:
- ISSN:
-
1932-6203
- Pubs id:
-
pubs:642047
- URN:
-
uri:06380110-4ad0-45f7-b34b-0278b28213dd
- UUID:
-
uuid:06380110-4ad0-45f7-b34b-0278b28213dd
- Local pid:
- pubs:642047
- Language:
- English
- Keywords:
- Copyright holder:
- Dunning et al.
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Dunning et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Experimental treatment of Ebola virus disease with brincidofovir
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