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Prostate cancer (PCa) risk variants and risk of fatal PCa in the national cancer institute breast and prostate cancer cohort consortium

Abstract:

Background Screening and diagnosis of prostate cancer (PCa) is hampered by an inability to predict who has the potential to develop fatal disease and who has indolent cancer. Studies have identified multiple genetic risk loci for PCa incidence, but it is unknown whether they could be used as biomarkers for PCa-specific mortality (PCSM). Objective To examine the association of 47 established PCa risk single-nucleotide polymorphisms (SNPs) with PCSM. Design, setting, and participants We include...

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Journal:
European Urology More from this journal
Volume:
65
Issue:
6
Pages:
1069-1075
Publication date:
2014-01-01
DOI:
EISSN:
1873-7560
ISSN:
0302-2838
Pubs id:
pubs:465456
UUID:
uuid:062f1042-e067-4938-9c79-78a52c18afe2
Local pid:
pubs:465456
Source identifiers:
465456
Deposit date:
2014-06-17

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