Journal article icon

Journal article

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01E on blood stage immunity in young Kenyan children

Abstract:

Background: RTS,S/AS01 E, the most advanced malaria vaccine confers partial immunity. The vaccine-induced pre-erythrocytic immunity reduces exposure to blood-stage parasites, delaying acquisition of antibodies to blood-stage antigens. However, the duration of this effect is unknown.
Methods: We measured, by enzyme-linked immunosorbent assay, IgG-antibodies to 4 Plasmodium falciparum blood-stage antigens (AMA1, MSP142, EBA...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
SE-Other
Department:
External
Role:
Author
ORCID:
0000-0002-8977-0030
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-8377-5466
Publisher:
F1000Research
Journal:
Wellcome Open Research More from this journal
Volume:
4
Article number:
42
Publication date:
2019-03-05
Acceptance date:
2019-02-12
DOI:
ISSN:
2398-502X
Pmid:
31168483
Language:
English
Keywords:
Pubs id:
pubs:1011825
UUID:
uuid:0627ffe3-b269-4863-b266-a7204a3db610
Local pid:
pubs:1011825
Source identifiers:
1011825
Deposit date:
2019-06-18

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP