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Impaired endothelial responses in apparently healthy young people associated with subclinical variation in blood pressure and cardiovascular phenotype.

Abstract:

BACKGROUND: A phenomenon of endothelial impairment, independent of classical cardiovascular risk factors, has been observed in young people. We identified subjects with persistently reduced, or declining, endothelial function during adolescence and early adulthood, without apparent cardiovascular risk, and investigated the clinical relevance of this finding. METHODS: Endothelial vasomotor responses were assessed by brachial artery flow-mediated dilatation (FMD) at age 15 years in 47 subjects ...

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Publication status:
Published

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Publisher copy:
10.1038/ajh.2011.176

Authors


Lewandowski, AJ More by this author
Kylintireas, I More by this author
Cunnington, C More by this author
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Journal:
American journal of hypertension
Volume:
25
Issue:
1
Pages:
46-53
Publication date:
2012-01-05
DOI:
EISSN:
1941-7225
ISSN:
0895-7061
URN:
uuid:06246766-a0af-4658-a6bf-a65e7fce56dd
Source identifiers:
186495
Local pid:
pubs:186495

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