- Abstract:
-
Post-mortem measures of Abeta amyloid deposition correlate only weakly with cognitive dysfunction antemortem. We tested the hypothesis that functional reorganization forms a critical intermediary step between Abeta amyloid-associated brain injury and clinical disease expression. Fifteen patients with early-stage probable Alzheimer's disease (AD) and 16 cognitively intact controls participated in this combined functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) ...
Expand abstract - Publisher copy:
- 10.1093/brain/awm133
-
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- Journal:
- Brain : a journal of neurology
- Volume:
- 130
- Issue:
- Pt 8
- Pages:
- 2055-2069
- Publication date:
- 2007-08-05
- DOI:
- EISSN:
-
1460-2156
- ISSN:
-
0006-8950
- URN:
-
uuid:06241f22-cc21-4980-b0b4-c8c27c810f76
- Source identifiers:
-
429457
- Local pid:
- pubs:429457
- Copyright date:
- 2007
Journal article
Abeta amyloid deposition in the language system and how the brain responds.
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