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Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis.

Abstract:

Background

Mildly elevated lactate levels (i.e., 1–2 mmol/L) are increasingly recognized as a prognostic finding in critically ill patients. One of several possible underlying mechanisms, microcirculatory dysfunction, can be assessed at the bedside using sublingual direct in vivo microscopy. We aimed to evaluate the association between relative hyperlactatemia, microcirculatory flow, and outcome.

Methods

This study was a predefined subanalysis of a multicenter int...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13054-017-1842-7

Authors


Publisher:
BioMed Central
Journal:
Critical Care More from this journal
Volume:
21
Issue:
1
Pages:
255
Publication date:
2017-10-01
Acceptance date:
2017-09-15
DOI:
EISSN:
1466-609X
ISSN:
1364-8535
Pmid:
29047411
Language:
English
Keywords:
Pubs id:
pubs:742521
UUID:
uuid:061b526d-93c0-4215-be5d-83eee2771c2b
Local pid:
pubs:742521
Source identifiers:
742521
Deposit date:
2018-02-13

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