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The role of previously unmeasured organic acids in the pathogenesis of severe malaria.

Abstract:

Severe falciparum malaria is commonly complicated by metabolic acidosis. Together with lactic acid (LA), other previously unmeasured acids have been implicated in the pathogenesis of falciparum malaria.In this prospective study, we characterised organic acids in adults with severe falciparum malaria in India and Bangladesh. Liquid chromatography-mass spectrometry was used to measure organic acids in plasma and urine. Patients were followed until recovery or death.Patients with severe malaria ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13054-015-1023-5

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Grant:
Major Overseas Programme Core Grant number 089275/Z/09/Z
Publisher:
BioMed Central Publisher's website
Journal:
Critical care (London, England) Journal website
Volume:
19
Issue:
1
Pages:
317
Chapter number:
ARTN 317
Publication date:
2015-01-01
DOI:
EISSN:
1466-609X
ISSN:
1364-8535
URN:
uuid:06192f30-b033-4226-80b6-2a40ddad3fed
Source identifiers:
545500
Local pid:
pubs:545500
Language:
English

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