- Abstract:
-
Severe falciparum malaria is commonly complicated by metabolic acidosis. Together with lactic acid (LA), other previously unmeasured acids have been implicated in the pathogenesis of falciparum malaria.In this prospective study, we characterised organic acids in adults with severe falciparum malaria in India and Bangladesh. Liquid chromatography-mass spectrometry was used to measure organic acids in plasma and urine. Patients were followed until recovery or death.Patients with severe malaria ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.1MB)
-
- Publisher copy:
- 10.1186/s13054-015-1023-5
-
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- Grant:
- Major Overseas Programme Core Grant number 089275/Z/09/Z
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Critical care (London, England) Journal website
- Volume:
- 19
- Issue:
- 1
- Pages:
- 317
- Chapter number:
- ARTN 317
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
-
1466-609X
- ISSN:
-
1364-8535
- URN:
-
uuid:06192f30-b033-4226-80b6-2a40ddad3fed
- Source identifiers:
-
545500
- Local pid:
- pubs:545500
- Language:
- English
- Copyright holder:
- Herdman et al.
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Herdman et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Journal article
The role of previously unmeasured organic acids in the pathogenesis of severe malaria.
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+ Wellcome Trust
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