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Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study.

Abstract:

Background

Artemisinin resistance in Plasmodium falciparumextends across Southeast Asia where it is associated with worsening partner drug resistance and a decline in the efficacy of frontline artemisinin-based combination therapy. Dihydroartemisinin-piperaquine (DP) is an essential component of preventive and curative treatment in the region, but its therapeutic efficacy has fallen in Cambodia.

Methods

A prospective clinical and parasitological evaluation of DP wa...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12936-016-1240-7

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
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Department of International Development More from this funder
Wellcome Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
15
Issue:
1
Pages:
185
Publication date:
2016-03-05
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:06146bda-09cd-4477-9f70-fcf2e3a0fb31
Source identifiers:
627574
Local pid:
pubs:627574

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