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Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial

Abstract:

Background: Bevacizumab has been suggested to have similar effectiveness to ranibizumab for treatment of neovascular age-related macular degeneration. The Inhibition of VEGF in Age-related choroidal Neovascularisation (IVAN) trial was designed to compare these drugs and different regimens. Here, we report the findings at the prespecified 2-year timepoint. Methods: In a multicentre, 2×2 factorial, non-inferiority randomised trial, we enrolled adults aged at least 50 years with active, previous...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(13)61501-9

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
382
Issue:
9900
Pages:
1258-1267
Publication date:
2013-01-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Source identifiers:
415330
Language:
English
UUID:
uuid:06121ca7-8e18-4e11-864a-4aa0255262e1
Local pid:
pubs:415330
Deposit date:
2014-08-29

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