Journal article
Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid
- Abstract:
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Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a serious global health concern. Since their emergence in the mid-1970s multi-drug resistant (MDR) S. Typhi now dominate drug sensitive equivalents in many regions. MDR in S. Typhi is almost exclusively conferred by self-transmissible IncHI1 plasmids carrying a suite of antimicrobial resistance genes. We identified over 300 single nucleotide polymorphisms (SNPs) within conserved regions of the IncHI1 plasmid, and g...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 689.8KB)
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- Publisher copy:
- 10.1371/journal.pntd.0001245
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Neglected Tropical Diseases Journal website
- Volume:
- 5
- Issue:
- 7
- Pages:
- ARTN e1245
- Publication date:
- 2011-07-19
- Acceptance date:
- 2011-06-03
- DOI:
- EISSN:
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1935-2735
- ISSN:
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1935-2727
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:170214
- UUID:
-
uuid:06017070-578f-4f27-a00f-7182cd01699e
- Local pid:
- pubs:170214
- Source identifiers:
-
170214
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Holt et al
- Copyright date:
- 2011
- Notes:
- Copyright: © 2011 Holt et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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