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CTD kinase associated with yeast RNA polymerase II initiation factor b.

Abstract:

A kinase activity specific for the C-terminal repeat domain (CTD) of RNA polymerase II is associated with nearly homogeneous yeast general initiation factor b by three criteria: cofractionation on the basis of size and charge and coinactivation by mild heat treatment. The kinase phosphorylates the CTD at multiple sites in a processive manner. Factor b may possess a DNA-dependent ATPase activity as well. Both kinase and DNA-dependent ATPase activities exhibit the same nucleotide requirements a...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Genomics Consortium
Role:
Author
Journal:
Cell More from this journal
Volume:
67
Issue:
6
Pages:
1223-1230
Publication date:
1991-12-01
DOI:
EISSN:
1097-4172
ISSN:
0092-8674
Language:
English
Keywords:
Pubs id:
pubs:34184
UUID:
uuid:0600c2cf-5b27-4cd8-a4d8-15b63fea79ad
Local pid:
pubs:34184
Source identifiers:
34184
Deposit date:
2012-12-19

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