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Intracerebroventricular injection of a nitric oxide synthase inhibitor does not affect long-term slope potentiation in vivo.

Abstract:

Although there is evidence from in vitro studies to suggest that NO synthesis may be involved in the induction of hippocampal LTP, other in vitro studies and experiments conducted in vivo have provided conflicting results. In agreement with previous work conducted in this laboratory using an i.p. route of administration, this paper reports that i.c.v. injections of the NO synthase inhibitor, N omego-nitro-L-arginine methyl ester (L-NAME), at a dose sufficient to inhibit hippocampal NO synthas...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Neuropharmacology
Volume:
33
Issue:
11
Pages:
1387-1397
Publication date:
1994-11-01
DOI:
EISSN:
1873-7064
ISSN:
0028-3908
Source identifiers:
27998
Language:
English
Keywords:
Pubs id:
pubs:27998
UUID:
uuid:0600220e-73e5-45b9-8e1e-e09f71228226
Local pid:
pubs:27998
Deposit date:
2012-12-19

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