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Paradoxical decrease in isoprostane and increase in superoxide dismutase following CPAP withdrawal in OSA.

Abstract:

We thank Monneret and Bonnefont-Rousselot for their commentary. Our controlled trial design overcomes most of their concerns of course; any failure of assay techniques would not have produced a biased result, but in fact would have decreased the chances of finding any between-group effects. In our study we observed a statistically significant decrease in urinary F2-isoprostanes following the withdrawal of CPAP treatment in patients with obstructive sleep apnoea (CPAP), in a randomised, two-we...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1183/13993003.01725-2015

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Publisher:
European Respiratory Society
Journal:
European Respiratory Journal More from this journal
Volume:
47
Issue:
3
Pages:
1014-1015
Publication date:
2016-02-29
Acceptance date:
2015-10-25
DOI:
EISSN:
1399-3003
ISSN:
0903-1936
Language:
English
Pubs id:
pubs:609110
UUID:
uuid:05f772e6-3a5a-4c63-a4ee-eb6ac7d16dd6
Local pid:
pubs:609110
Source identifiers:
609110
Deposit date:
2016-03-29

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