The relationship between callosal axons and cortical neurons in the planum temporale: alterations in schizophrenia.

Journal article

The relationship between "connectivity" measures such as DTI and the cellular alterations in the cortex that give rise to those connections remains unclear. Cytoarchitectural changes in the planum temporale (PT) suggest impaired layer III feedforward projection neurons in schizophrenia. Altered hemispheric asymmetry of the PT has been reported in patients, along with altered white matter density in the corpus callosum, and there is anomalous activation of the PT during auditory hallucinations...

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Authors: Simper, R; Walker, M; Black, G; Di Rosa, E; Crow, T

• Publication status: Published
• Journal: Neuroscience research
• Volume: 71
• Issue: 4
• Pages: 405-410
• Publication date: 2011-12-01
• DOI: 10.1016/j.neures.2011.08.007
• EISSN: 1872-8111
• ISSN: 0168-0102
• Language: English
• Keywords: Neural Pathways; Cell Count; Male; Autopsy; Corpus Callosum; Humans; Female; Pyramidal Cells; Axons; Schizophrenia; Aged