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Phylogenetic relationships and differential selection pressures among genotypes of dengue-2 virus

Abstract:

To elucidate the processes controlling the emergence and spread of dengue-2 virus (DEN-2) we examined the evolution of viral isolates sampled from both local (Viet Nam) and global populations. Our phylogenetic analysis, incorporating envelope (E) glycoprotein sequences from 147 isolates of DEN-2, provided a more complete picture of viral diversity, with a newly defined "Cosmopolitan" genotype having a near global distribution and two other genotypes restricted to Asia. By analyzing rates of s...

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Publisher copy:
10.1006/viro.2002.1447

Authors


Twiddy, SS More by this author
Farrar, JJ More by this author
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Journal:
Virology
Volume:
298
Issue:
1
Pages:
63-72
Publication date:
2002
DOI:
ISSN:
0042-6822
URN:
uuid:05cd83b0-52c6-4802-8693-517b6e7b5589
Source identifiers:
92741
Local pid:
pubs:92741

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