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Clinical and serological study of myasthenia gravis using both radioimmunoprecipitation and cell-based assays in a South Asian population

Abstract:

Background Identification of autoantibodies has defined distinct clinico-immuno-pathological subtypes of myasthenia gravis (MG) such as AChR-antibody-positive-MG and MuSK-antibody-positive-MG. The use of more sensitive assays such as the cell-based assay (CBA) is expected to reduce the proportion of seronegative-MG. We studied the seroprevalence of AChR and MuSK antibodies using both radioimmunoprecipitation (RIA) and CBA amongst MG patients in Sri Lanka and related their antibody status to t...

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Publisher copy:
10.1016/j.jns.2014.05.037

Authors


Publisher:
Elsevier
Journal:
Journal of the Neurological Sciences
Volume:
343
Issue:
1-2
Pages:
82-87
Publication date:
2014-08-15
DOI:
EISSN:
1878-5883
ISSN:
0022-510X
Language:
English
Keywords:
Pubs id:
pubs:478908
UUID:
uuid:05c9eda2-134e-40af-839c-78b1a4d26285
Local pid:
pubs:478908
Source identifiers:
478908
Deposit date:
2014-08-16

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