- Abstract:
-
PURPOSE OF REVIEW: Vascularized composite allograft (VCA) transplantation restores defects to a degree not possible by conventional techniques. However, it is limited by the need for long-term immunosuppression and high rates of acute rejection directed against skin. There is therefore a need for a therapy that may shift the risk-benefit ratio in favour of VCA transplantation. Regulatory T cells (Tregs) are a subset of T cells with potent immunoregulatory properties and the potential to promo...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1097/mot.0000000000000139
-
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- Publisher:
- Lippincott Williams and Wilkins
- Journal:
- Current opinion in organ transplantation
- Volume:
- 19
- Issue:
- 6
- Pages:
- 558-565
- Publication date:
- 2014-12-05
- DOI:
- EISSN:
-
1531-7013
- ISSN:
-
1087-2418
- URN:
-
uuid:05c81fa2-d322-4ff0-962e-177af0e8650c
- Source identifiers:
-
488159
- Local pid:
- pubs:488159
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
The potential role for regulatory T-cell therapy in vascularized composite allograft transplantation.
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