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An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib

Abstract:

A rare variant of renal cell carcinoma (RCC) with a translocation involving Xp11.2 has become increasingly recognized as a separate entity in the 2004 World Health Organization (WHO) kidney carcinoma classification. These tumors predominantly affect children and young adults and tend to present with advanced stage disease. Although reported to be indolent in children, adult cases run a more aggressive course. Little is known about their natural history, prognosis and response to therapy. We r...

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology, Molecular Medicine
Roberts, ISD More by this author
Sullivan, M More by this author
Protheroe, A More by this author
Journal:
Urologic Oncology: Seminars and Original Investigations
Volume:
29
Issue:
6
Pages:
821-824
Publication date:
2011-11-05
DOI:
EISSN:
1873-2496
ISSN:
1078-1439
URN:
uuid:05c6d1a7-52f0-414f-aee1-8ab6373768cf
Source identifiers:
206450
Local pid:
pubs:206450
Language:
English

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