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Efficacy of β blockers in patients with heart failure plus atrial fibrillation: An individual-patient data meta-analysis

Abstract:

Background Atrial fibrillation and heart failure often coexist, causing substantial cardiovascular morbidity and mortality. β blockers are indicated in patients with symptomatic heart failure with reduced ejection fraction; however, the efficacy of these drugs in patients with concomitant atrial fibrillation is uncertain. We therefore meta-analysed individual-patient data to assess the efficacy of β blockers in patients with heart failure and sinus rhythm compared with atrial fibrillation. Me...

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Authors


Kotecha, D More by this author
Altman, DG More by this author
Manzano, L More by this author
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Publisher:
Lancet Publishing Group
Journal:
The Lancet
Volume:
384
Issue:
9961
Pages:
2235-2243
Publication date:
2014-12-27
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:05bfaac0-f0c6-4679-99eb-0b308c84f2dc
Source identifiers:
502926
Local pid:
pubs:502926
Language:
English

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